Genetic Testing for Colorectal Cancer | Everything you need to know

Genetic Testing for Colorectal Cancer | Everything you need to know

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What is Genetic Testing for Colorectal Cancer?


Hey, health champs! Today, we're talking about Genetic Testing for Colorectal Cancer – might sound a bit technical, but I promise, we're keeping it simple.


What's Genetic Testing for Colorectal Cancer?

In simple terms, it's like a genetic map helping us understand the chances of colorectal cancer. Think of it as checking your genes for any hints or red flags that might suggest a risk.


Breaking It Down: Everyday Talk

Imagine your genes are the instruction manual for your body. Genetic Testing for Colorectal Cancer is like proofreading that manual for any errors that could signal a risk for colorectal cancer. It's like having a heads-up system for your health.


Why does this matter? Stick around, and we'll chat about why this testing is like having a roadmap to keep your colorectal health on track!


Statistics of Colorectal Cancer in Malaysia

In Malaysia, colorectal cancer ranks as the third most common cancer, constituting 13.5% of new cases in 2020. With approximately 18,000 new cases annually, it disproportionately affects individuals aged 50 and above, emphasizing the need for early detection and prevention measures.

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Genetics and Colorectal Cancer

In the genetic world of colorectal cancer, key actors like APC and TP53 regulate growth and guard genetic integrity. Genes such as MSH2, MLH1, MYH, and SMAD4 join this dance, influencing cancer development.


Imbalances or mutations in these genes heighten colorectal cancer risk. While genetic variations don't solely dictate risk, they contribute to the complex factors influencing susceptibility to this disease.

Who Should Get Genetic Testing For Colorectal Cancer?

Not everyone treads the same genetic path, and as such, the question arises: who should contemplate the journey of genetic testing? Recognizing the indicators and understanding the risk factors aids in identifying individuals who stand to benefit most from this proactive approach.


Certain factors can elevate an individual's risk of developing colorectal cancer, making them prime candidates for genetic testing. These factors include:

  • A personal history of colorectal polyps or colorectal cancer

  • A family history of colorectal cancer or other hereditary cancer syndromes, such as Lynch syndrome or familial adenomatous polyposis (FAP)

  • A diagnosis of inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis

  • A personal history of certain non-colorectal cancers, such as endometrial, ovarian, or breast cancer

Colorectal Cancer Symptoms and Genetic Testing: What to Know

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Colorectal cancer often gives out signals, and catching them early is important for better care.

  • Bowel Habit Changes

Pay attention if your usual bathroom habits, like how often you go or the texture, change.

  • Unexplained Weight Loss

If you're losing weight without trying, it might be a sign of something going on.

  • Abdominal Discomfort

If you regularly feel cramps or discomfort in your belly, it's worth checking out.

  • Blood in Stool

Any bleeding from your back passage or in your poop needs attention, even if it's not always visible.

  • Fatigue and Anemia

Watch for persistent tiredness, pale skin, and weakness, which may indicate an issue that needs investigation.

  • Diagnostic Techniques

Tests like colonoscopies, blood tests, and imaging help doctors find out what might be going on.

  • Genetic Predisposition

Some people have a higher chance of colorectal cancer due to their family history. Genetic tests can reveal this risk.

  • Empowering Your Health

Understanding these signs is a good start. Early detection through screenings, lifestyle changes, and knowing your genetic risk can help you take charge of your colorectal health.

The Process of Colorectal Cancer Genetic Testing

Genetic testing for colorectal cancer is a straightforward process that typically involves the following steps:

  1. Ordering a DNA testing kit: You can order a DNA testing kit from an online website or through your healthcare provider. The kit will include instructions on how to collect a saliva sample and return it to the lab for testing.

  2. Collecting a saliva sample: Once you receive your DNA testing kit, you will collect a saliva sample using the provided swab and instructions. The process is simple and painless.

  3. Returning the saliva sample: After collecting your saliva sample, you will seal the sample tube and return it to the lab using the provided prepaid postage.

  4. Receiving your test results: You will typically receive your test results within 18-21 business days. Your test results will be sent to you securely through an online portal.

  5. Booking a one-on-one consultation: Once you receive your test results, you will schedule a one-on-one consultation with a genetic counselor or healthcare provider to discuss your results in detail.

Understanding Genetic Testing for Colorectal Cancer Results
Your genetic test results will indicate whether or not you have any genetic markers that increase your risk of developing colorectal cancer. There are two main types of genetic test results:

  • Positive results

Having these means you have markers increasing your risk. But, it doesn't mean you'll definitely get colorectal cancer.

  • Negative results

These show you don't have known markers increasing your risk. Still, it's crucial to follow recommended colorectal cancer screening guidelines.


A positive genetic test result leads to a personalized plan, involving more screenings, preventive surgeries, and lifestyle changes. Even with a negative result, following recommended screening guidelines is vital, considering factors like lifestyle and the environment. Genetic insights empower personalized prevention, shaping a future where colorectal cancer is a conquerable challenge.


Integrating Genetic Testing for Colorectal Cancer Information into Prevention

Now that we know our genes, let's make them work for a healthy heart. It's about creating simple plans, changing habits based on genes, and teaming up with health experts for an all-around approach.

  • Tailored Prevention Plans:

Know your genetic risk to tailor your health plan. For high risk, consider more frequent screenings like colonoscopies or fecal tests. Early detection prevents colorectal cancer. Act now for a healthier future.

  • Lifestyle Modifications

Making informed choices matters. Adopting a healthy diet, regular exercise, and avoiding smoking significantly lowers colorectal cancer risk. Working together with healthcare pros ensures your genetic info is part of your overall care plan.

  • Collaborative Care Approach

Open communication and shared decision-making between you and healthcare pros build comprehensive care plans. Addressing both genetic and lifestyle factors empowers you to make choices that keep you healthy.


Try Out Revive Wellness’ All-In-One Test!

Unlock proactive well-being with the Origene all-in-one genetic screening test from Revive Wellness. In just 18 days, this user-friendly kit explores crucial genes like APC and TP53. Beyond diagnosis, it becomes your compass for personalized prevention and testing plans. Tailor lifestyle adjustments to genetic risks, collaborating with healthcare pros for a holistic health approach. Act now—let your genes guide your journey to proactive well-being.